台灣牛群之單譜症雜合型頻率檢測
林德育 陳若菁 吳松鎮 李光復 楊德威 黃金山 曾青雲 蕭宗法 劉秀洲 張菊犁 黃鈺嘉 吳明哲
台灣省畜產試驗所
單譜症(Deficiency of Uridine Monophosphate Synthase，直譯為尿核甞單磷酸鹽合成�狗吤０g，國際上簡稱為 DUMPS)，是一種會導至牛胚胎早期死亡(約受孕後四十日)的遺傳缺陷。為了解單譜症在台灣牛隻之分布情形，本試驗共檢測 4 個民間牧場(南部及北部各兩場)與來自北部與東部地區參與 DHI計畫的自留小公牛，共 795頭荷蘭乳牛，以及台灣省畜產試驗所恒春分所 139頭台灣黃牛及70 頭布拉曼牛。在 795頭荷蘭乳牛中僅檢測出 1頭雜合型牛(0.13 %)，顯示此一遺傳疾病對本省乳牛之影響不大，而在所有檢測之台灣黃牛與布拉曼牛中亦均不帶有此一不良基因。
關鍵語：台灣、尿核甞單磷酸鹽合成�狗吤０g、單譜症。
LOW INCIDENCE OF DEFICIENCY OF URIDINE
MONOPHOSPHATE
SYNTHASE CARRIERS AMONG CATTLE OF TAIWAN
D. Y. Lin, J. C. Chen, S. C. Wu, K. F. Lee, T. W. Yang, C. S.
Huang, C. Y. Tseng,
T. F. Shiao, H. C. Liu, C. L. Chang, Y. C. Huang and M. C. Wu
Taiwan Livestock Research Institute
DUMPS, the acronym for Deficiency of Uridine Monophosphate Synthase, is a lethal inherited disorder of cattle. Homozygous recessive genotype results in embryonic mortality around 40 days post-conception. In this investigation, two sample sets were used to estimate the carrier frequency of DUMPS. First sample set was 795 Holsteins of which cows with few heifers and calves were from four DHI farms located in the north and south of Taiwan, and young bulls were from north and east of Taiwan. The second sample set was 139 Taiwan Yellow Cattle and 70 Brahmas from Heng-Chun Station, Taiwan Livestock Research Institute. Only one carrier cow was found in 795 Holsteins, and no carrier was found for Taiwan Yellow cattle and Brahma. With less than .2%(1/795=. 013%) carrier, DUMPS is not a significant genetic disease in Taiwan.
Key Words: Taiwan, Deficiency of Uridine Monophosphate Synthase, DUMPS.